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Relationship Between Calving Rate and Concentration of Hormones and Blood Metabolites During Pregnancy in Post-Induction Pasundan Cows GnRH

Received: 2 February 2021    Accepted: 10 February 2021    Published: 23 February 2021
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Abstract

Twenty Pasundan heifers were used in the study to find out calving rates related to the concentration of hormones and metabolites of the mother's blood during the farm. The experimental mother cow was given a combination of the hormone prostaglandin F2α as much as 5 ml per head and gonadotropin realising hormone (GnRH) of 2.5 ml per head intramuscular to uniformize fertility conditions and improve fertility. The mother cow is immediately carried out artificial insemination 2 times with an interval of 6 hours. All experimental cows were given forage basalt food and adlibitum drinking water. Pregnancy examination is carried out on the 60th and 150th days of post-insemination using the rectal palpation method. The observed variables in the form of calving rate were related to plasma concentrations of the hormones progesterone (P), estrogen (E), and blood metabolites levels β-OH butyric (BHBA), blood urea nitrogen (BUN), and non-esterified fatty acids (NEFA). The results showed that in Garut calving average rate of 90%, the plasma concentration of hormone progesterone 4.73±0.28 ng/ml and estrogen 24.59±1.91 pg/ml higher than Bogor with an average calving rate of 70%, the plasma concentration of progesterone hormone 3.46±0.71ng/ml and estrogen 21.67±1.57 pg/ml. The concentration of BHBA, BUN, and NEFA for Bogor region respectively was 12.33±1.81 mg dl-1; 23.70±2.40 mg dL; 1.85±0.25 mmol L-1) higher than Garut in a row is 10.17±1.25*mg dl-1, 22.70±2.70mg dL; 1.76±0.37mmol L-1). The results of regression analysis showed that the relationship of calving rate (CR) with the concentration of hormones conceptus estrogen (E) and progesterone (P) in garut region has a real form of linear relationship (P<0.05) by following the equation Calving rate=4772 +0.232 Estrogen + 0.643 Progesterone - 0.074 BHBA + 0.335 NEFA - 0.082 BUN with a coefficient of determination of 43.65%, while for Bogor region according to Calving regression rate=5,590+ 0.010 Estrogen +0.638 Progesterone - 0.231 BHBA + 1.11NEFA – 0.105 BUN with a coefficient of determination of 16.34%. It was concluded that calving rate is strongly influenced by the concentration of the hormones progesterone and estrogen, as well as having a close relationship with the condition of the mother blood metabolite during the pregnancy.

Published in International Journal of Animal Science and Technology (Volume 5, Issue 1)
DOI 10.11648/j.ijast.20210501.15
Page(s) 27-31
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Pasundan Cows, Synchronization, Calving Rate, Hormones, Blood Metabolite

References
[1] E. N. Setiawati, D. M. Saleh, and M. Sumaryadi. 2018. Kinerja Reproduksi Sapi Pasundan Di Jawa Barat. Pros. Semin. Teknol. dan Agribisnis Peternak. VI, 2018.
[2] Niswender, DG., JL Juengel., PJ. Silva., MK, Rollison and EW. McIntosh. 2000. Mechanism of controlling the function and life span of the corpus luteum. Physiol Rev 80: 1–29, 2000.
[3] Wilson. ME and Ford SP. 2000. Effect of estradiol-17 administration during the time of conceptus elongation on placental size at term in the Meishan pig. J Anim Sci 78: 1047–1052.
[4] Frastantie, D., M. Agil and L. I. Tumbelaka. 2019. Deteksi Kehamilan Dini pada Sapi Perah dengan Pemeriksaan Ultrasnography (USG) dan Analisis Hormo Steroid. Acta Vet. Indones. 7 (2): 9–16.
[5] Pemayun, T. G. 2014“. Waktu Inseminasi Buatan yang Tepat pada Sapi Bali dan Kadar. Progesteron pada Sapi Bunting. J. Vet 15 (3): 425–430.
[6] Geisert, R. D and RAM. Schmitt. 2002. Early Embryonic Survival in Pig: Can it be improved ?. J. Anim. Sci 80: 54–85.
[7] Bindari, Y. R., S. Shrestha, N. Shrestha, and T. N. Gaire. 2013. Effects of Nutrition on Reproduction. Adv Appl Sci Res 4 (1) 421–429.
[8] Wahyudi, L., T. Sulistiawati and S. Wahyuningsih. 2013. Tampilan reproduksi sapi perah pada berbagai paritas di Desa Kemiri Kecamatan Jabung Kabupaten Malang. J. Ternak Trop.
[9] Pradhan R, K Oshima, Y Ochiai, T Kojima, N Yamamoto, M. E. Ghanem, and N. Nakagoshi. 2008. Effect of total cholesterol, glucose and blood urea nitrogen on embryo quality inpost-partum superovulated suckling Japanese black cattle. Reprod. Med. Biol 7 (2): 55–62.
[10] Guadarrama, C. A., M. A. Pasqoier., J. P. Dourmad., A. Prunier and H. Quesnel. 2002. Protein Restriction in Lactating Sows: Effects on Metabolic State, Somatotropic Axis and Reproductive Performance after Weaning. J. Anim. Sci 80: 3286–3300.
[11] Han, H. C., N. C. Stickland and D. A. Owen. 2004. Maternal Nutrient Restriction Alters Gen Expression in the Ovin Fetal Hearth. J. Phisiology 558: 111-121.
[12] Van den Brand, H., M. J. W. Heetkamp., N. M. Soede., J. W. Schrama, and B. Kemp. 2000. Energy Balance of Lactating Primiparous Sows as Affected by Feeding Level and Dietary Source J, Anim. Sci 78: 1520–1528.
[13] Gross, J., H. A. Van Dorland., R. M. Brukmaier and F. J. Schwarz. 2011. Performance and Metabolic Profile of Dairy Cows During a Lactational and Deliberately Induced Negative Energy Balance with Subsequent Realimentation. J. Dairy Sci 94 (4): 1820-1830.
[14] Junior, M. V. C. F., A. V. Pires, M. V. Biehl, M. H. Santos, D. M. Polizel, D. D. Nepomuceno, R. Sartori, J. B. B. Filho, J. R. S. Goncalves and M. L. Day. 2016. Luteolysis in Bos indicucows on Days 5 and 7 of estrous cycle with varying doses of PGF2α. Theriogenology 86 (5): 1268–1274.
[15] Mondal, S and B. S. Parkash. 2003. Peripheral plasma progesterone concentration in relation to estrus expression in Sahiwal cows. Indian J. Physiol. Pharmacol 47: 27–34.
[16] Lim, H. J., J. K. Son, H. B. Yoon, K. S. Baek, T. I. Kim, Y. S. Jung and E. G. Kwon. 2014. Physical Properties of Estrus Mucus in Relation to Conception Rates in Dairy Cattle. J. Emb. Trans. 29 (2): 157-161.
[17] Murray RK, Granner DK, Mayes PA, & Rodwell VW. 2003. Biokimia Harper. Edisi ke-25. Jakarta (ID): EGC. 2003.
[18] Julie, M. H and R. O. Thomas. 2013. Using physiological markers to defect health and production problems in transition dairy cows. WCDC Adv. Dairy Technol 25: 329–33.
[19] Van Saun, R. J. 2000. Blood profiles as indicators of nutritional status. Adv. Dairy Tech 12: 401–410.
[20] Shaka, M., M. Shamesdini and F. Mohamad-Zadeh. 2006. Serum biochemistry values in Raini Goat of Iran,” J Vet Med 6 (12): 33–45.
[21] Saleh, N., E. Mahmud and E. Waded. 2011. Interactions Between Insulin Like Growth Factor 1, Thyroid Hormones and Blood Energy Metabolites in Cattle With Postpartum Inactive Ovaries. Nat. Sci 9 (5): 56–63.
[22] Gaja AO, Al-Dahash SYA, Raju GS, Kubota C. 2013. Ultrasonic assessment of corpora lutea and plasma proGesterone levels in early pregnant and non pregnant cows. J. Adv. Biomed. Patol. Res. 3 (1): 19-24.
[23] Waldmann A, Kurykin J, Jaakma U, Kaart T, Aidnik M, Jalakas M, Majas L and Padrik P. 2006. The effects of ovarian function on estrus synchronization with PGF in dairy cows. Theriogenology 66: 1364–1374.
[24] Wiltbank MC, Souza AH, Giordano JO, Nascimento AB, Vasconcelos JM, Pereira MHC, Fricke PM, Surjus RS, Zinsly FCS, Carvalho PD, Bender RW, Sartori R. 2012. Positive and negative effects of progesterone during AI protocols in lactating dairy cattle. Anim. Reprod 9 (3): 231–241.
[25] Prabowo. 2010. Teknik Sinkronisasi Estrus Pada Sapi. Bagian Reproduksi dan Obstetri Fakultas Kedokteran Hewan Universitas Gajah Mada. Yogyakarta.
[26] Hafez, B and E. S. E. Hafez. 2000. Reproduction in Farm Animals. 7th. ed. Lea and Febiger Co., Philadelphia, USA.
[27] Jainudeen, M. R. and E. S. E., Hafez. 2008. Cattle and buffalo. Reproduction in farm animals. 7th Edition. Edited by Hafez E. S. E. Lippincott Williams & Wilkins. Maryland. USA. 159.
[28] Hurley W. L. 2001. Mammary gland growth in the lactating sow. Livest. Prod. Sci 70: 149–157.
[29] Wetterman RP, Hill GM & Boyd ME. 2003. Reproductive performance of postpartum beef cows after short-term calf separation and dietary energy and protein supplementation. Theriogenology 4: 433–443.
[30] Salem MB., Djemali M., Kayouli C & Majdoub A. 2006. A review of enviromental and management factors affecting the productive performance of Holstein Friesian dairy herds in Tunisia. Livest. Res. Rural Dev 18 (4): 123–129.
[31] Adewuyi, A. A., E. Gruys and F. J. C. M. V. Eerdenburg. 2005. Non Esterified Fatty Acids (NEFA) in Dairy Cattle. Vet. Quarterly. 7 (3): 117-126.
[32] Stocco, C., T. Carlos and G. Geula. 2007. The molecular control of corpus luteum formation, function, and regression. Endocr. Soc 117–149.
[33] Khan, S., A. Thangavel and S. Selvasubramaniyan. 2010. lood biochemical profile in repeat breeding cows. J. Vet. Anim. Sci 4: 90-102.
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  • APA Style

    Euis Nia Setiawati, Mas Yedi Sumaryadi, Vony Armelia. (2021). Relationship Between Calving Rate and Concentration of Hormones and Blood Metabolites During Pregnancy in Post-Induction Pasundan Cows GnRH. International Journal of Animal Science and Technology, 5(1), 27-31. https://doi.org/10.11648/j.ijast.20210501.15

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    Euis Nia Setiawati; Mas Yedi Sumaryadi; Vony Armelia. Relationship Between Calving Rate and Concentration of Hormones and Blood Metabolites During Pregnancy in Post-Induction Pasundan Cows GnRH. Int. J. Anim. Sci. Technol. 2021, 5(1), 27-31. doi: 10.11648/j.ijast.20210501.15

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    AMA Style

    Euis Nia Setiawati, Mas Yedi Sumaryadi, Vony Armelia. Relationship Between Calving Rate and Concentration of Hormones and Blood Metabolites During Pregnancy in Post-Induction Pasundan Cows GnRH. Int J Anim Sci Technol. 2021;5(1):27-31. doi: 10.11648/j.ijast.20210501.15

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  • @article{10.11648/j.ijast.20210501.15,
      author = {Euis Nia Setiawati and Mas Yedi Sumaryadi and Vony Armelia},
      title = {Relationship Between Calving Rate and Concentration of Hormones and Blood Metabolites During Pregnancy in Post-Induction Pasundan Cows GnRH},
      journal = {International Journal of Animal Science and Technology},
      volume = {5},
      number = {1},
      pages = {27-31},
      doi = {10.11648/j.ijast.20210501.15},
      url = {https://doi.org/10.11648/j.ijast.20210501.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijast.20210501.15},
      abstract = {Twenty Pasundan heifers were used in the study to find out calving rates related to the concentration of hormones and metabolites of the mother's blood during the farm. The experimental mother cow was given a combination of the hormone prostaglandin F2α as much as 5 ml per head and gonadotropin realising hormone (GnRH) of 2.5 ml per head intramuscular to uniformize fertility conditions and improve fertility. The mother cow is immediately carried out artificial insemination 2 times with an interval of 6 hours. All experimental cows were given forage basalt food and adlibitum drinking water. Pregnancy examination is carried out on the 60th and 150th days of post-insemination using the rectal palpation method. The observed variables in the form of calving rate were related to plasma concentrations of the hormones progesterone (P), estrogen (E), and blood metabolites levels β-OH butyric (BHBA), blood urea nitrogen (BUN), and non-esterified fatty acids (NEFA). The results showed that in Garut calving average rate of 90%, the plasma concentration of hormone progesterone 4.73±0.28 ng/ml and estrogen 24.59±1.91 pg/ml higher than Bogor with an average calving rate of 70%, the plasma concentration of progesterone hormone 3.46±0.71ng/ml and estrogen 21.67±1.57 pg/ml. The concentration of BHBA, BUN, and NEFA for Bogor region respectively was 12.33±1.81 mg dl-1; 23.70±2.40 mg dL; 1.85±0.25 mmol L-1) higher than Garut in a row is 10.17±1.25*mg dl-1, 22.70±2.70mg dL; 1.76±0.37mmol L-1). The results of regression analysis showed that the relationship of calving rate (CR) with the concentration of hormones conceptus estrogen (E) and progesterone (P) in garut region has a real form of linear relationship (P<0.05) by following the equation Calving rate=4772 +0.232 Estrogen + 0.643 Progesterone - 0.074 BHBA + 0.335 NEFA - 0.082 BUN with a coefficient of determination of 43.65%, while for Bogor region according to Calving regression rate=5,590+ 0.010 Estrogen +0.638 Progesterone - 0.231 BHBA + 1.11NEFA – 0.105 BUN with a coefficient of determination of 16.34%. It was concluded that calving rate is strongly influenced by the concentration of the hormones progesterone and estrogen, as well as having a close relationship with the condition of the mother blood metabolite during the pregnancy.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Relationship Between Calving Rate and Concentration of Hormones and Blood Metabolites During Pregnancy in Post-Induction Pasundan Cows GnRH
    AU  - Euis Nia Setiawati
    AU  - Mas Yedi Sumaryadi
    AU  - Vony Armelia
    Y1  - 2021/02/23
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ijast.20210501.15
    DO  - 10.11648/j.ijast.20210501.15
    T2  - International Journal of Animal Science and Technology
    JF  - International Journal of Animal Science and Technology
    JO  - International Journal of Animal Science and Technology
    SP  - 27
    EP  - 31
    PB  - Science Publishing Group
    SN  - 2640-1312
    UR  - https://doi.org/10.11648/j.ijast.20210501.15
    AB  - Twenty Pasundan heifers were used in the study to find out calving rates related to the concentration of hormones and metabolites of the mother's blood during the farm. The experimental mother cow was given a combination of the hormone prostaglandin F2α as much as 5 ml per head and gonadotropin realising hormone (GnRH) of 2.5 ml per head intramuscular to uniformize fertility conditions and improve fertility. The mother cow is immediately carried out artificial insemination 2 times with an interval of 6 hours. All experimental cows were given forage basalt food and adlibitum drinking water. Pregnancy examination is carried out on the 60th and 150th days of post-insemination using the rectal palpation method. The observed variables in the form of calving rate were related to plasma concentrations of the hormones progesterone (P), estrogen (E), and blood metabolites levels β-OH butyric (BHBA), blood urea nitrogen (BUN), and non-esterified fatty acids (NEFA). The results showed that in Garut calving average rate of 90%, the plasma concentration of hormone progesterone 4.73±0.28 ng/ml and estrogen 24.59±1.91 pg/ml higher than Bogor with an average calving rate of 70%, the plasma concentration of progesterone hormone 3.46±0.71ng/ml and estrogen 21.67±1.57 pg/ml. The concentration of BHBA, BUN, and NEFA for Bogor region respectively was 12.33±1.81 mg dl-1; 23.70±2.40 mg dL; 1.85±0.25 mmol L-1) higher than Garut in a row is 10.17±1.25*mg dl-1, 22.70±2.70mg dL; 1.76±0.37mmol L-1). The results of regression analysis showed that the relationship of calving rate (CR) with the concentration of hormones conceptus estrogen (E) and progesterone (P) in garut region has a real form of linear relationship (P<0.05) by following the equation Calving rate=4772 +0.232 Estrogen + 0.643 Progesterone - 0.074 BHBA + 0.335 NEFA - 0.082 BUN with a coefficient of determination of 43.65%, while for Bogor region according to Calving regression rate=5,590+ 0.010 Estrogen +0.638 Progesterone - 0.231 BHBA + 1.11NEFA – 0.105 BUN with a coefficient of determination of 16.34%. It was concluded that calving rate is strongly influenced by the concentration of the hormones progesterone and estrogen, as well as having a close relationship with the condition of the mother blood metabolite during the pregnancy.
    VL  - 5
    IS  - 1
    ER  - 

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Author Information
  • Cinagara Animal Health Training Center, Kabupaten Bogor, Indonesia

  • Faculty of Animal Science, Jenderal Soedirman University, Purwokerto, Indonesia

  • Faculty of Animal Science, Jenderal Soedirman University, Purwokerto, Indonesia

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